RT Journal Article
SR Electronic
T1 Management of myelofibrosis: a survey of current practice in the United Kingdom
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 1124
OP 1127
DO 10.1136/jclinpath-2012-201056
VO 65
IS 12
A1 Moosa Rashid Qureshi
A1 Cathy MacLean
A1 Mary Frances McMullin
A1 Claire Harrison
YR 2012
UL http://jcp.bmj.com/content/65/12/1124.abstract
AB Aims To investigate the experience of clinicians in the management of patients with myelofibrosis, current treatment options and their utility. Methods We used an internet-based survey Results Of 105 respondents (mostly consultants), 79% identified bothersome symptoms as the most common issue to be addressed, while for 19%, lack of efficacy of treatment fell into this category. The survey found that a wide variety of treatments are employed but with poor perceived efficacy. Conclusions This is the first UK based assessment of management of myelofibrosis. Perspectives may evolve with the inception of novel therapeutics in this field , but clinical guidelines for effective management currently recommend a wide variety of agents and suggest a limited likely success rate.