RT Journal Article
SR Electronic
T1 Extreme hyperferritinaemia; clinical causes
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 438
OP 440
DO 10.1136/jclinpath-2012-201090
VO 66
IS 5
A1 Martin A Crook
A1 Patrick L C Walker
YR 2013
UL http://jcp.bmj.com/content/66/5/438.abstract
AB There are many causes of raised serum ferritin concentrations including iron overload, inflammation and liver disease to name but a few examples. Cases of extreme hyperferritinaemia (serum ferritin concentration equal to or greater than 10 000 ug/l) are being reported in laboratories but the causes of this are unclear. We conducted an audit study to explore this further. Extreme hyperferritinaemia was rare with only 0.08% of ferritin requests displaying this. The main causes of extreme hyperferritinaemia included multiple blood transfusions, malignant disease, hepatic disease and suspected Still's disease.