TY - JOUR T1 - The diagnostic challenge of congenital dyserythropoietic anaemia: two cases of ‘CDA type II’ JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 367 LP - 369 DO - 10.1136/jclinpath-2013-201779 VL - 67 IS - 4 AU - Srivasavi Dukka AU - May-Jean King AU - Quentin A Hill Y1 - 2014/04/01 UR - http://jcp.bmj.com/content/67/4/367.abstract N2 - The congenital dyserythropoietic anaemias (CDAs) are a group of rare hereditary disorders characterised by ineffective erythropoiesis and morphological abnormalities in the erythroblasts. Patients may present with jaundice or with symptoms of anaemia, gall stones or iron overload. The diagnosis can be challenging and cases have been confused with haemolytic anaemia, haemochromatosis or a haemoglobinopathy. A delayed diagnosis can lead to inappropriate treatment or delayed management of iron overload. We present two patients previously diagnosed as CDA type II in whom the diagnosis was revised to CDA type I and to hereditary spherocytosis. The conditions are compared and the approach to diagnosis is discussed. ER -