PT  - JOURNAL ARTICLE
AU  - Ni Chen
AU  - Ling Nie
AU  - Jing Gong
AU  - Xueqin Chen
AU  - Miao Xu
AU  - Min Chen
AU  - Qiao Zhou
TI  - Gains of chromosomes 7 and 17 in tubulocystic carcinoma of kidney: two cases with fluorescence in situ hybridisation analysis
AID  - 10.1136/jclinpath-2014-202363
DP  - 2014 Nov 01
TA  - Journal of Clinical Pathology
PG  - 1006--1009
VI  - 67
IP  - 11
4099  - http://jcp.bmj.com/content/67/11/1006.short
4100  - http://jcp.bmj.com/content/67/11/1006.full
SO  - J Clin Pathol2014 Nov 01; 67
AB  - Tubulocystic carcinoma (TCC) is a very rare renal tumour with unique gross and microscopic features, alternatively considered as low-grade collecting duct carcinoma. Recent studies favoured distinction of TCC from collecting duct carcinoma, and some cases of TCC synchronously coexisting with other renal cell tumour subtypes were described. We report here two new cases of pure (case 1) or mixed (case 2) TCC with fluorescence in situ hybridisation (FISH) analysis, which showed gains of chromosomes 7 and 17 in the pure TCC of case 1, as well as in the TCC and the papillary renal cell carcinoma (PRCC) components in case 2. These data may further support the notion that TCC is more closely related to PRCC.