RT Journal Article SR Electronic T1 Concordance between digital pathology and light microscopy in general surgical pathology: a pilot study of 100 cases JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 1052 OP 1055 DO 10.1136/jclinpath-2014-202491 VO 67 IS 12 A1 Joseph P Houghton A1 Aaron J Ervine A1 Sarah L Kenny A1 Paul J Kelly A1 Seamus S Napier A1 W Glenn McCluggage A1 Maureen Y Walsh A1 Peter W Hamilton YR 2014 UL http://jcp.bmj.com/content/67/12/1052.abstract AB Aim (1) A pilot study to determine the accuracy of interpretation of whole slide digital images in a broad range of general histopathology cases of graded complexity. (2) To survey the participating histopathologists with regard to acceptability of digital pathology. Materials and methods Glass slides of 100 biopsies and minor resections were digitally scanned in their entirety, producing digital slides. These cases had been diagnosed by light microscopy at least 1 year previously and were subsequently reassessed by the original reporting pathologist (who was blinded to their original diagnosis) using digital pathology. The digital pathology-based diagnosis was compared with the original glass slide diagnosis and classified as concordant, slightly discordant (without clinical consequence) or discordant. The participants were surveyed at the end of the study. Results There was concordance between the original light microscopy diagnosis and digital pathology-based diagnosis in 95 of the 100 cases while the remaining 5 cases showed only slight discordance (with no clinical consequence). None of the cases were categorised as discordant. Participants had mixed experiences using digital pathology technology. Conclusions In the broad range of cases we examined, digital pathology is a safe and viable method of making a primary histopathological diagnosis.