RT Journal Article
SR Electronic
T1 Cutaneous angiosarcoma: a current update
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 917
OP 925
DO 10.1136/jclinpath-2017-204601
VO 70
IS 11
A1 Elina Shustef
A1 Viktoryia Kazlouskaya
A1 Victor G Prieto
A1 Doina Ivan
A1 Phyu P Aung
YR 2017
UL http://jcp.bmj.com/content/70/11/917.abstract
AB Cutaneous angiosarcoma (cAS) is a rare malignant neoplasm with variable clinical presentation. Although a distinct vascular tumour, cAS shares many overlapping histopathological features with other vasoformative and epithelioid tumours or ‘mimickers’. cAS shows aggressive behaviour and carries a grave prognosis, thus early diagnosis is of paramount importance to achieve the best possible outcomes. Recently, several genetic studies were conducted leading to the identification of novel molecular targets in the treatment of cAS. Herein, we present a comprehensive review of cAS with discussion of its clinical, histopathological and molecular aspects, the differential diagnosis, as well as current therapies including ongoing clinical trials.