PT  - JOURNAL ARTICLE
AU  - Antonio La Gioia
AU  - Maurizio Fumi
AU  - Paola Pezzati
AU  - Fiamma Balboni
AU  - Ylenia Pancione
AU  - Lucia Rocco
AU  - Silvia Sale
AU  - Maria Bombara
AU  - Marcello Fiorini
AU  - Fabiana Fiorini
AU  - Vincenzo Rocco
TI  - Automatic wedge smears preparation may cause traumatic morphological changes in peripheral blood cells
AID  - 10.1136/jclinpath-2017-204580
DP  - 2018 Feb 01
TA  - Journal of Clinical Pathology
PG  - 168--171
VI  - 71
IP  - 2
4099  - http://jcp.bmj.com/content/71/2/168.short
4100  - http://jcp.bmj.com/content/71/2/168.full
SO  - J Clin Pathol2018 Feb 01; 71
AB  - In recent years, several automated analysers that prepare and stain blood smears have been introduced in clinical laboratories. Despite the use of instrumental settings based on physical characteristic of individual samples, traumatic injuries of neutrophil and lymphocytes can be observed. Some samples present a very high percentage of damaged cells, allowing the speculation that a cellular susceptibility may enhance mechanical traumatism. These artefacts can puzzle morphological evaluation in both traditional and digitised microscopy; in addition, unskilled operators can be misled.