TY - JOUR T1 - Fungal sinusitis in simultaneous pancreas-kidney transplant JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 720 LP - 720 DO - 10.1136/jclinpath-2018-205258 VL - 72 IS - 10 AU - Daniel W Santos AU - Henrique Proença AU - Jose O Medina-Pestana AU - Érika B Rangel Y1 - 2019/10/01 UR - http://jcp.bmj.com/content/72/10/720.abstract N2 - A 56-year-old man was submitted to a simultaneous pancreas-kidney transplant 6 years ago. He received induction therapy with thymoglobulin, and maintenance immunosuppressive regimen consisted of tacrolimus (trough levels 6–8 ng/mL), prednisone and mycophenolate. Pulmonary tuberculosis was treated in the first year post-transplant. He reported cough, nasal congestion, and anosmia for at least 6 months. No fever was documented. Chest CT was normal. Sinus CT showed opacification in the right maxillary and ethmoidal sinuses without bone involvement. A biopsy was taken during endoscopic ethmoidectomy and antrostomy sinus surgery.Review the high-quality, interactive digital Aperio slides at http://virtualacp.com/JCPCases/jclinpath-2018-205258.R1_1/,http://virtualacp.com/JCPCases/jclinpath-2018-205258.R1_2/, http://virtualacp.com/JCPCases/jclinpath-2018-205258.R1_3/ and consider your diagnosis.Post-transplant lymphoproliferative disorderHyalohyphomycosis (Aspergillosis or Fusariosis)AdenovirusHistoplasmosisMucormycosisThe correct answer is after the discussion.The differential diagnosis of dry cough, nasal congestion and anosmia … ER -