RT Journal Article SR Electronic T1 Flagging performance of Sysmex XN-10 haematology analyser for malaria detection JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 676 OP 677 DO 10.1136/jclinpath-2019-206382 VO 73 IS 10 A1 Cécile Dumas A1 Pauline Tirard-Collet A1 Fanélie Mestrallet A1 Sandrine Girard A1 Laurent Jallades A1 Stéphane Picot A1 Anne-Lise Bienvenu YR 2020 UL http://jcp.bmj.com/content/73/10/676.abstract AB Aim The aim was to assess the flagging performance of Sysmex XN-10 haematology analyser for malaria detection through the parasitic red blood cell (‘pRBC’) alarm.Methods We retrospectively studied 584 blood samples performed on the Sysmex XN-10 analyser that were tested for malaria. Sensitivity, specificity, positive and negative predictive values, and prevalence were established for the pRBC alarm.Results Sensitivity, specificity, and positive and negative predictive values for the pRBC flag were 7.8%, 100%, 100% and 87.7%, respectively. The prevalence of pRBC flag of 0.026% in the overall population was significantly different from the prevalence of 1.027% in the population tested for malaria.Conclusions Considering the excellent specificity and the low prevalence of the flag in the overall population, we suggest, in case of the presence of pRBC flag, the implementation of a rapid review of the blood smear looking for Plasmodium, mostly if the patient had fever and had not been tested for malaria.