PT  - JOURNAL ARTICLE
AU  - Cornelia Margaret Szecsei
AU  - Jon D Oxley
TI  - Errors in prostate core biopsy diagnosis in an era of specialisation and double reporting
AID  - 10.1136/jclinpath-2020-206726
DP  - 2021 May 01
TA  - Journal of Clinical Pathology
PG  - 327--330
VI  - 74
IP  - 5
4099  - http://jcp.bmj.com/content/74/5/327.short
4100  - http://jcp.bmj.com/content/74/5/327.full
SO  - J Clin Pathol2021 May 01; 74
AB  - Aim To examine the effects of specialist reporting on error rates in prostate core biopsy diagnosis.Method Biopsies were reported by eight specialist uropathologists over 3 years. New cancer diagnoses were double-reported and all biopsies were reviewed for the multidisciplinary team (MDT) meeting. Diagnostic alterations were recorded in supplementary reports and error rates were compared with a decade previously.Results 2600 biopsies were reported. 64.1% contained adenocarcinoma, a 19.7% increase. The false-positive error rate had reduced from 0.4% to 0.06%. The false-negative error rate had increased from 1.5% to 1.8%, but represented fewer absolute errors due to increased cancer incidence.Conclusions Specialisation and double-reporting have reduced false-positive errors. MDT review of negative cores continues to identify a very low number of false-negative errors. Our data represents a ‘gold standard’ for prostate biopsy diagnostic error rates. Increased use of MRI-targeted biopsies may alter error rates and their future clinical significance.