TY - JOUR T1 - Errors in prostate core biopsy diagnosis in an era of specialisation and double reporting JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 327 LP - 330 DO - 10.1136/jclinpath-2020-206726 VL - 74 IS - 5 AU - Cornelia Margaret Szecsei AU - Jon D Oxley Y1 - 2021/05/01 UR - http://jcp.bmj.com/content/74/5/327.abstract N2 - Aim To examine the effects of specialist reporting on error rates in prostate core biopsy diagnosis.Method Biopsies were reported by eight specialist uropathologists over 3 years. New cancer diagnoses were double-reported and all biopsies were reviewed for the multidisciplinary team (MDT) meeting. Diagnostic alterations were recorded in supplementary reports and error rates were compared with a decade previously.Results 2600 biopsies were reported. 64.1% contained adenocarcinoma, a 19.7% increase. The false-positive error rate had reduced from 0.4% to 0.06%. The false-negative error rate had increased from 1.5% to 1.8%, but represented fewer absolute errors due to increased cancer incidence.Conclusions Specialisation and double-reporting have reduced false-positive errors. MDT review of negative cores continues to identify a very low number of false-negative errors. Our data represents a ‘gold standard’ for prostate biopsy diagnostic error rates. Increased use of MRI-targeted biopsies may alter error rates and their future clinical significance. ER -