RT Journal Article SR Electronic T1 Laboratory interpretative comments and guidance: clinical and operative outcomes on moderate to severe hyponatraemia patient management JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP jclinpath-2021-207611 DO 10.1136/jclinpath-2021-207611 A1 Blanca Montero-San-Martín A1 Paloma Oliver A1 Pilar Fernandez-Calle A1 Juan J Sánchez-Pascuala Callau A1 Mariana Díaz Almirón A1 María J Alcaide Martín A1 Belen Fernández-Puntero A1 Marta Duque Alcorta A1 José M Valero Recio A1 Alejandro Martín Quirós A1 María de Ceano-Vivas la Calle A1 Julia Martín Sánchez A1 Begoña Rivas Becerra A1 Cristina Vega Cabrera A1 Marta Melgosa Hijosa A1 Antonio Buno Soto YR 2021 UL http://jcp.bmj.com/content/early/2021/09/23/jclinpath-2021-207611.abstract AB Aims Hyponatraemia is the most common body fluid disorders but often goes unnoticed. Our laboratory incorporated a standardised procedure to help clinicians detect moderate/severe hyponatraemia. The study aims were to evaluate the outcomes on patient care and clinicians’ satisfaction.Methods The study, observational and retrospective, included 1839 cases, adult and paediatric patients, with sodium concentration <130 mmol/L. The procedure consisted of interpretative comments in the emergency and core laboratories report and the point-of-care testing blood gas network report. We evaluated hyponatraemia length in two equal periods: before and after the implementation. We conducted a survey addressed to the staff of the clinical settings involved to know their satisfaction.Results The median hyponatraemia length decreased significantly from 4.95 hours (2.08–16.57) in the first period to 2.17 hours (1.06–5.39) in the second period. The lack of hyponatraemia patients follow-up was significantly less after the procedure implementation. The survey was answered by 92 (60 senior specialists and 32 residents) out of 110 clinicians surveyed. Ninety of them (98%) answered positively.Conclusions We have demonstrated the reduction in the time for diagnosing and management by physicians, the higher uniformity in the time required to solve hyponatraemia episodes following our laboratory procedure and the clinicians’ satisfaction.All data relevant to the study are included in the article. We collected study data from the laboratory information system of our hospital.