TY - JOUR T1 - Adipophilin: roles in physiology and pathology JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 98 LP - 102 DO - 10.1136/jcp-2022-208677 VL - 76 IS - 2 AU - Feng-Zeng Li AU - Sheng Fang Y1 - 2023/02/01 UR - http://jcp.bmj.com/content/76/2/98.abstract N2 - Adipophilin (ADRP/ADPH/PLIN2), an adipocyte differentiation-related protein, is highly expressed at a very early time during the differentiation of adipocytes. It assists in the formation and maintenance of intracellular lipid droplets and plays a role in regulating the physiological functions of the body. More and more studies indicate that it is involved in the occurrence and development of a variety of glycolipid metabolic diseases and tumours. In this review, we comprehensively stated the expression and functions of adipophilin and introduced its roles in physiology and pathology. ER -