TY - JOUR T1 - Predictors of risk of relapse in classic Hodgkin lymphoma JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 414 LP - 417 DO - 10.1136/jcp-2022-208552 VL - 76 IS - 6 AU - Jonathan R Fromm AU - Claire Tang AU - Kikkeri N Naresh Y1 - 2023/06/01 UR - http://jcp.bmj.com/content/76/6/414.abstract N2 - Using multiparametric flow cytometric analysis, in a cohort of 62 patients with classic Hodgkin lymphoma having a median follow-up period of 69.5 months, we found—patients who experienced primary resistance or disease relapse (DR) had lower percentage of rosetted Hodgkin Reed-Sternberg cells (HRS-cells) as compared with patients who achieved sustained complete remission (SCR) (p=0.022); patients >35 years of age had higher percentage of HRS-cells (p=0.017) and lower percentage of B cells (p=0.017) and the nodular sclerosis subtype had higher percentage of B-cells (p=0.046) and activated B-cells (p=0.03). The proportion of SCR and DR subsets did not differ by histological subtypes, disease stage or age groups. ER -