Clinical and histological features and outcome of primary malignant lymphomas of the bladder
Age/Sex | Clinical history | Histological diagnosis | Immunophenotype | Follow up |
---|---|---|---|---|
F, female; M, male; MALT, mucosa associated lymphoid tissue. | ||||
66/F | Large bladder mass that clinically resembled stage T3 transitional cell carcinoma. No lymphadenopathy on physical examination or computed tomography | Low grade MALT-type lymphoma | CD20+ | Alive after 1 year |
79/F | Haematuria. Multiple bladder tumours on cystoscopy. No evidence of tumour elsewhere | Low grade MALT-type lymphoma | CD20+ | No follow up |
59/F | First diagnosed in 1995. Defaulted follow up. Re-presented 1998. Solid necrotic tumour anterior wall of bladder, clinically stage T2–T3 | Low grade MALT-type lymphoma | CD20+ CD43+ | Alive with disease after 3 years |
84/F | Presented with intermittent haematuria over the previous 2 years. Cystoscopy showed mucosal congestion but no obvious tumour. Repeat cystoscopy 3 weeks later showed tumour obscuring the right ureteric orifice, clinically stage T3. There was no lymphadenopathy and no evidence of tumour elsewhere. Macroscopically thought to be invasive transitional cell carcinoma | Diffuse large B cell lymphoma | CD20+ | Died of disease after 6 months |
67/M | Painless haematuria. Irregular tumour mass in right side of bladder. Treated with radiotherapy and chemotherapy. Now has recurrent solid growth in posterior wall of bladder. No evidence of disease elsewhere | Diffuse large B cell lymphoma | CD20+ CD30+ | Alive with disease after 16 years |
80/F | Presented with a 3 month history of intermittent haematuria. Impaired renal function. Cystoscopy showed a ring of tumour obstructing the right urethral meatus. Treated with radiotherapy. Bone marrow uninvolved. No evidence of lymphadenopathy or tumour elsewhere | Diffuse large B cell lymphoma | CD20+ | Alive and well after 3 years 8 months |