Table 1

Clinical, morphological, and biological data of the entire study group T1–4 N0–2 M0 (n = 307)

p21waf negativep21waf positiveTotal
n%n%n% p Value
Univariate statistical calculation using χ2 test.
Receptor status: positive, ER positive and/or PR positive; negative, ER negative and PR negative; detection by immunohistochemistry.
Lymph nodes were removed in 295 cases, steroid hormone receptor status was determined in 302 women, PCNA in 301, Her2/neu expression in 298, and p53 expression in 299 samples.
ER, oestrogen receptor; NS, not significant; PCNA, proliferating cell nuclear antigen; PR, progesterone receptor.
Age (years)
    < 507323.83511.410835.2
    > 5013544.06420.819964.8NS
Menopausal status
Tumour size (cm)
    < 28026.13511.411537.5
    > 2–510233.24514.714749.9
    > 5268.5196.24514.7NS
Nodal status
    1–3 nodes6923.4279.29632.5
    > 4 nodes4013.6258.56522.0NS
Tumour grade
Receptor status
    < 10%9531.64113.613645.2
    > 50%3712.33110.36822.60.029