Table 3

Clinical, morphological, and biological data of node positive women T1–4 N+ M0 (n = 161)

p21waf negativep21waf positiveTotal
n%n%n% p Value
Univariate statistical calculation using χ2 test.
Receptor status: positive, ER positive and/or PR positive; negative, ER negative and PR negative; detection by immunohistochemistry.
Steroid hormone receptor status was determined in 158 women, PCNA in 158, Her2/neu expression in 156, and p53 expression in 156 samples.
ER, oestrogen receptor; NS, not significant; PCNA, proliferating cell nuclear antigen; PR, progesterone receptor.
Age (years)
    < 503421.12213.75634.8
    > 507546.63018.610565.2NS
Menopausal status
Tumour size (cm)
    < 23018.61710.64729.2
    > 2–55735.42515.58250.9
    > 52213.7106.23219.9NS
Tumour grade
Receptor status
    < 10%4629.11912.06541.1
    > 50%2616.51811.44427.8NS