MIC ranges for yeast isolates as determined by Etest and spectrophotometric broth microdilution methods
| Antifungals | Methods | MIC range (mg/litre) | MIC50 (mg/litre) | MIC90 (mg/litre) |
|---|---|---|---|---|
| Amphotericin B | Etest RPMI/casitone (lab 1) | 0.125 to 1/0.03 to 0.25 | 0.25/0.125 | 0.5/0.125 |
| Etest RPMI/casitone (lab 2) | 0.125 to 1/0.06 to 0.5 | 0.125/0.125 | 0.5/0.25 | |
| Broth microdilution (lab 3) | 0.06 to ≥4 | 0.25 | 0.5 | |
| Fluconazole | Etest RPMI/casitone (lab 1) | 0.125 to 64/0.5 to 64 | 0.25/2 | 32/8 |
| Etest RPMI/casitone (lab 2) | 0.25 to ≥256/1 to ≥256 | 0.5/2 | 32/64 | |
| Broth microdilution (lab 3) | 0.125 to 64 | 0.25 | 32 | |
| Itraconazole | Etest RPMI/casitone (lab 1) | 0.03 to ≥32/0.06 to ≥32 | 0.25/0.25 | ≥32/8 |
| Etest RPMI/casitone (lab 2) | 0.03 to ≥32/0.06 to ≥32 | 0.25/0.125 | ≥32/≥32 | |
| Broth microdilution (lab 3) | 0.008 to 2 | 0.008 | 1 |