The AP-2α, AP-2β, and AP-2γ protein and AP-2α mRNA expression and histological features of the adenomas
| Case | Degree of dysplasia | AP-2α protein expression | AP-2β protein expression | AP-2γ protein expression | AP-2α mRNA expression |
|---|---|---|---|---|---|
| *Corresponding mRNA protein positive and negative areas; ‡AP-2α positivity in <5% of nuclei. | |||||
| The percentages presented describe cytoplasmic staining in adenoma cells. | |||||
| mRNA expression: –, negative; +, focally positive; ++, diffusely positive, moderate; +++, diffusely positive, strong. | |||||
| 1 | 1 | 0% | 80% | 10% | + |
| 2 | 2 | 40% | 70% | 40% | ++*‡ |
| 3 | 2 | 60% | 60% | 10% | +++*‡ |
| 4 | 3 | 30% | 10% | 30% | +* |
| 5 | 2 | 20% | 60% | 10% | + |
| 6 | 2 | 10% | 70% | 10% | +* |
| 7 | 2 | 10% | 30% | 20% | + |
| 8 | 1 | 20% | 20% | 5% | + |
| 9 | 2 | 30% | 60% | 0% | ++*‡ |
| 10 | 1 | 70% | 20% | 0% | + |
| 11 | 2 | 30% | 80% | 60% | +* |
| 12 | 1 | 30% | 50% | 0% | – |
| 13 | 1 | 10% | 85% | 20% | – |