Distribution of staining of different catenins as related to clinicopathological factors
α-Catenin | β-Catenin | γ-Catenin | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
<10% | 10–90% | ≥90% | N | p Value | <10% | 10–90% | ≥90% | N | p Value | <10% | 10–90% | ≥90% | N | p Value | |
Numbers are percentages of cases identified in the three groups: <10%; 10–90%; ≥90%. | |||||||||||||||
Histology | |||||||||||||||
Squamous cell carcinoma | 24 | 49 | 27 | 146 | 16 | 69 | 15 | 145 | 15 | 64 | 21 | 146 | |||
Adenocarcinoma | 5 | 33 | 62 | 58 | <0.0001 | 10 | 24 | 66 | 58 | <0.0001 | 13 | 29 | 58 | 59 | <0.0001 |
Anaplastic/large cell carcinoma | 37 | 41 | 22 | 27 | 23 | 58 | 19 | 26 | 43 | 42 | 15 | 26 | |||
Histological grade | |||||||||||||||
Grade I | 20 | 20 | 60 | 15 | 6 | 44 | 50 | 16 | 6 | 38 | 56 | 16 | |||
Grade II | 11 | 47 | 42 | 96 | 0.005 | 12 | 54 | 34 | 94 | 0.007 | 9 | 58 | 33 | 96 | 0.005 |
Grade III | 25 | 48 | 27 | 88 | 18 | 60 | 22 | 87 | 21 | 53 | 26 | 85 | |||
Stage | |||||||||||||||
Stage I | 19 | 43 | 38 | 146 | 16 | 56 | 28 | 149 | 16 | 53 | 31 | 147 | |||
Stage II–IV | 24 | 47 | 29 | 81 | 0.6 | 15 | 55 | 30 | 76 | 0.2 | 20 | 52 | 28 | 80 | 0.6 |
Tumour size | |||||||||||||||
T1 | 18 | 39 | 43 | 61 | 14 | 49 | 37 | 63 | 18 | 49 | 33 | 63 | |||
T2–4 | 21 | 46 | 33 | 165 | 0.4 | 16 | 60 | 24 | 161 | 0.2 | 17 | 54 | 29 | 164 | 0.8 |
Lymph node status | |||||||||||||||
NO | 19 | 44 | 37 | 154 | 15 | 58 | 27 | 156 | 15 | 55 | 30 | 154 | |||
N1–3 | 24 | 44 | 32 | 72 | 0.6 | 16 | 53 | 31 | 68 | 0.7 | 22 | 48 | 30 | 73 | 0.4 |