Table 1

Correlation between SPF variables and disease outcome in breast carcinoma

	Disease free survival			Overall survival
Variables	n	No. recurrences	p Value	No. deaths	p Value
SPF, S-phase fraction.
% Average SPF
(whole series)			0.0003		0.0010
<5.9	119	8		4
≥5.9	120	29		21
% SPF tertiles
(whole series)			0.0034		0.0054
<4.5	78	4		1
4.5–9.2	78	12		8
≥9.2	78	19		14
% SPF tertiles
(diploid tumours)			0.4625		0.1600
<3	37	2		0
3–4.7	50	3		2
≥4.7	42	5		4
% SPF tertiles
(aneuploid tumours)			0.9935		0.6834
<10	34	7		5
10–13	35	8		4
≥13	36	9		8
% Median SPF
(whole series)			0.0001		0.0003
<6.1	117	7		3
≥6.1	117	28		20
% Median SPF
(diploid tumours)			0.4468		0.1070
<3.8	66	4		1
≥3.8	63	6		5
% Median SPF
(aneuploid tumours)			0.1776		0.3887
<12	52	14		8
≥12	53	10		9