Table 1

Reactivity of Centres for Disease Control (Atlanta, Georgia, USA) prototype sera in six detection systems for anti-Ro, anti-La, anti-Sm, and anti-U1-RNP

Method
Prototype serumCIE-IHCIE-ComELISA-1ELISA-2ELISA-3WB-Com
Results are expressed as those specificities detected in each prototype serum.
ELISAs 1, 2, and 3 are from different manufacturers.
CIE-Com, countercurrent immunoelectrophoresis (commercial); CIE-IH, countercurrent immunoelectrophoresis (in house); ELISA, enzyme linked immunosorbent assay; RNP, ribonuclear protein; WB-Com, western blotting (commercial).
Anti-RoRoRoRoNegativeRoNegative
Anti-LaLaLaRo + LaLaRo + LaLa
Anti-SmSmSmSm/RNPSm/RNPSm/RNPSm
Anti-U1-RNPRNPRNPRNPRNPRNPRNP