Table 1

Loss of heterozygosity (LOH) in skin adnexal tumours

Type (no.)16p (D16s407)16q (D16s308)16q (D16s304)Overall LOH at 16q
The data are presented as number of cases exhibiting LOH/number informative for that marker (%).
*One case showed LOH at both 16q markers.
NI, not informative; no, number of cases studied.
Cylindroma (4)0/4 (0%)2/4 (50%)*2/3 (67%)*75%
Trichoepithelioma (2)0/1 (0%)NI1/2 (50%)50%
Apocrine hydrocystoma (4)0/3 (0%)0/3 (0%)1/3 (33%)33%
Eccrine spiradenoma (7)0/5 (0%)0/5 (0%)1/5 (20%)20%
Sebaceous adenoma (4)0/2 (0%)1/3 (33%)1/3 (33%)66%
Syringoma (7)1/5 (20%)0/3 (0%)1/5 (20%)20%
Eccrine hydrocystoma (5)1/4 (25%)0/5 (0%)0/4 (0%)0%
Trichofolliculoma (8)0/6 (0%)0/8 (0%)0/5 (0%)0%
Eccrine poroma (8)0/6 (0%)0/7 (0%)0/7 (0%)0%
Trichilemmoma (4)0/3 (0%)0/3 (0%)0/1 (0%)0%
Eccrine carcinoma (1)NI0/1 (0%)0/1 (0%)0%
Desmoplastic trichoepithelioma (1)0/1 (0%)NI0/1 (0%)0%
Basal cell carcinoma (9)0/5 (0%)1/8 (13%)0/5 (0%)13%
Squamous cell carcinoma (5)0/3 (0%)0/4 (0%)0/3 (0%)0%