Table 1

Clinicopathological features of patients with phaeochromocytoma or paraganglioma

						Expression
Case	Sex/age	Side	Site	Size (cm)	Malignant/ Benign	p53	Rb	mdm2	Func	Dx	Remarks
Expression: +, positive; 0, negative.
M, male; F, female; Func, functional tumour; Dx, clinical diagnostic; DOD, died of disease; AWD, alive with disease; PM, postmortem; OT, operation.
1	F/21	Right	Adrenal	3.0	Benign	0	+	0	Yes	Yes	–
2	M/57	Left	Adrenal	9.0	Malignant	0	0	0	Yes	Yes	DOD after 8 years
3	M/33	Right	Adrenal	3.5	Benign	0	0	0	Yes	Yes	–
4	F/30	Left	Adrenal	8.0	Benign	0	0	+	Yes	Yes	–
5	M/2	Right	Adrenal	3.0	Benign	+	0	0	Yes	No	–
6	M/52	Right	Adrenal	9.0	Benign	0	0	+	Yes	Yes	–
7	M/22	Left	Adrenal	5.0	Benign	0	0	+	Yes	Yes	–
8	M/36	Right	Adrenal	5.0	Malignant	0	0	0	Yes	Yes	DOD after 16 years
9	M/63	Right	Adrenal	8.0	Benign	0	0	+	Yes	Yes	–
10	F/35	Left	Adrenal	5.0	Malignant	0	0	0	Yes	Yes	AWD after 17 years
11	F/32	Right	Adrenal	8.5	Benign	0	0	+	Yes	Yes	Alive after 1 year
12	F/22	Right	Adrenal	8.0	Benign	0	+	+	Yes	Yes	–
13	F/18	Right	Adrenal	7.5	Benign	0	0	0	Yes	Yes	Alive after 4.3 years
14	M/26	Right	Adrenal	5.0	Benign	0	0	+	No	No	–
15	F/46	Right	Adrenal	8.0	Malignant	0	0	0	No	Yes	AWD after 3.2 years
16	F/40	Right	Adrenal	5.0	Benign	0	0	0	Yes	Yes	Alive after 5 months
17	M/59	Right	Adrenal	5.0	Benign	0	0	+	Yes	Yes	Alive after 11.6 years
18	F/62	Right	Adrenal	9.0	Benign	0	0	0	Yes	Yes	Alive after 1.2 years
19	M/53	Right	Adrenal	12.0	Benign	0	0	0	Yes	Yes	Alive after 1.3 years
20	M/38	Right	Adrenal	3.0	Benign	0	0	0	Yes	Yes	Alive after 12 years;
		Left	Adrenal	1.0							MEN2
21	F/32	Left	Adrenal	3.0	Benign	0	0	0	Yes	Yes	Alive after 10.6 years
22	F/34	Right	Adrenal	5.0	Benign	0	0	0	Yes	Yes	Alive after 9.1 years
23	F/58	Right	Adrenal	5.0	Benign	0	0	0	Yes	Yes	Alive after 7.3 years
24	M/54	Left	Adrenal	4.0	Benign	0	0	0	Yes	Yes	Alive after 6.1 years
25	M/65	Right	Adrenal	9.5	Benign	0	0	0	Yes	Yes	Alive after 4.6 years
26	M/42	Left	Adrenal	6.0	Malignant	0	0	+	Yes	Yes	Alive after 12.4 years
27	M/63	Right	Adrenal	8.0	Malignant	+	+	0	Yes	Yes	DOD after 2 years
		Left	Adrenal	4.5
28	M/48	Left	Adrenal	6.8	Benign	0	0	+	Yes	Yes	Alive after 2.8 years
29	F/62	Left	Adrenal	11.5	Malignant	0	0	0	No	No	Died shortly after OT
30	F/51	Right	Adrenal	2.5	Benign	0	0	+	No	Yes	Alive after 3.8 years;
		Left	Adrenal	1.7							MEN2
31	F/62	Right	Adrenal	6.0	Benign	0	0	+	Yes	Yes	Alive after 3.8 years
32	F/56	Right	Adrenal	2.0	Benign	0	0	0	Yes	Yes	Alive after 1 year
33	F/73	Right	Adrenal	8.0	Benign	0	0	+	Yes	Yes	Alive after 11 months
34	F/33	Right	Adrenal	2.0	Benign	0	0	+	Yes	Yes	Alive after 8 months
35	F/40	Right	Adrenal	11.0	Benign	+	+	0	Yes	Yes	Alive after 7 months;
		Left	Adrenal	4.5							MEN2
36	M/42	Left	Adrenal	1.0	Benign	0	0	+	No	No	Incidental PM finding
37	M/71	Right	Adrenal	13.0	Malignant	0	0	+	No	No	Incidental PM finding
38	M/50	Right	Adrenal	5.0	Benign	0	0	+	No	No	Incidental PM finding
39	F/47	Left	Adrenal	8.0	Benign	0	0	0	No	No	Incidental PM finding
40	M/50	Right	Carotid body	17.0	Malignant	0	0	0	No	No	Incidental PM finding
41	M/40	Right	Jaw	2.5	Benign	0	+	+	No	No	–
42	F/68	Right	Retroperitoneum	3.5	Benign	0	0	+	No	No	Died shortly after OT
43	F/39	Left	Middle ear	0.5	Benign	0	0	0	No	Yes	–
44	F/50	Right	Middle ear	0.5	Benign	0	+	+	No	Yes	–
45	M/63	Left	Jaw	0.5	Benign	0	+	+	No	No	–
46	M/25	Right	Carotid body	3.0	Benign	0	+	+	No	No	–
47	M/22	Left	Carotid body	3.0	Malignant	0	+	0	No	No	DOD after 13 years
48	F/26	Right	Carotid body	4.0	Benign	0	+	+	No	Yes	Alive after 16.4 years
		Left	Carotid body	2.5
49	F/39	Right	Middle ear	0.7	Benign	0	+	+	No	Yes	Alive after 12.3 years
50	F/60	Right	Middle ear	1.0	Benign	0	+	+	No	Yes	–
51	F/23	Right	Retroperitoneum	10.0	Malignant	0	0	+	Yes	Yes	DOD after 6.5 years
52	F/28	Left	Bladder	5.0	Malignant	0	0	+	Yes	No	AWD after 12.4 years
53	M/19	Right	Carotid body	3.5	Benign	0	0	+	No	No	Alive after 11.3 years
54	M/53	Right	Bladder	3.0	Benign	0	0	+	No	No	Alive after 10 years; with rectal carcinoid
55	F/21	Right	Carotid body	5.0	Benign	+	0	+	No	Yes	Brother had carotid body tumour;
		Left	Carotid body	2.0							alive after 8.8 years
56	M/34	Right	Carotid body	4.0	Benign	0	+	+	No	Yes	Sister had carotid body tumour;
		Left	Carotid body	2.0							alive after 8.3 years
57	M/35	Left	Base of skull	1.0	Benign	0	+	+	No	No	Alive after 6 years
58	F/28	Left	Carotid body	3.0	Benign	0	+	+	No	Yes	Alive after 5.2 years
59	M/31	Left	Carotid body	2.5	Benign	0	+	+	No	Yes	Alive after 5 years
60	F/30	Left	Carotid body	4.5	Benign	0	+	+	No	Yes	Alive after 4 years
		Right	Carotid body	4.0
61	F/85	Left	Retroperitoneum	0.6	Benign	0	+	+	No	No	Alive after 1.8 years
62	F/68	Left	Middle ear	0.2	Benign	0	+	+	No	Yes	Alive after 2.1 years
63	M/36	Left	Carotid body	3.5	Malignant	0	+	0	No	Yes	Alive after 1.7 years
64	M/59	Right	Retroperiotneum	7.0	Benign	0	+	0	No	No	Alive after 1.3 years
65	F/33	Right	Carotid body	3.0	Benign	0	+	0	No	Yes	Alive after 9 years