Table 1

Expression of Bcl-2, Bcl-XL, and Mcl-1 in normal, dysplastic, and malignant biliary epithelium

TissueNumber of samples (unless otherwise stated)Bcl-2 proteinBcl-XL proteinMcl-1 protein
CBD, resected common bile duct; GB, resected gall bladder.
Normal biliary epithelium7 (GB, 6; CBD, 1)NegativePositivePositive
Fresh cytology and brush samples10NegativePositivePositive
Biliary dysplasia3NegativePositivePositive
Cholangiocarcinoma51NegativePositivePositive
Human cholangiocarcinoma cell lines3NegativePositivePositive