Causes of neutropenia
XLA, X linked agammaglobulinaemia. |
Transient |
Chronic |
(1) Congenital neutropenias |
Failure of production (bone marrow) |
Severe chronic neutropenia |
Cyclic neutropenia |
Reticular dysgenesis |
(2) Associated with syndromes |
Primary immunodefeciencies: XLA, hyper-IgM |
Glycogen storage disease (1b) |
Shwachman diamond syndrome |
Cardioskeletal myopathy |
Onychotrichodysplasia |
Antibody mediated neutropenias |
Autoimmune neutropenia of infancy |
Alloimmune neonatal neutropenia |
Neonatal neutropenia owing to autoimmune disease in mother |
Autoimmune neutropenia seen in association with primary specific immunodeficiencies |
Idiopathic |
Chronic benign neutropenia |