Table 2

Conditions associated with subnormal neutrophil chemotaxis

Defects in the neutrophil
Neonatal neutrophils
Neutrophil actin dysfunction
Syndromes: Schwachman, glycogenosis type 1b, Chediak Higashi, and hyper-Ig E
Acrodermatitis enteropathica (zinc deficiency)
Specific granule deficiency
Chromosome 7 abnormalities
Direct inhibition of neutrophil chemotaxis
Juvenile periodontitis
Immune complex diseases
Wiskott Aldrich syndrome
Bone marrow transplant
Drugs such as corticosteroids, amphotericin B, antithymocyte globulin
Granulomatous diseases such as sarcoidosis
Malignancies
Defective generation of chemotactic factors
Familial complement deficiencies of alternative or classical pathway