Table 3

Treatment induced morphological changes in non-neoplastic tissue

Tissue typeHistological features after chemoradiotherapyN
Blood vesselsIntimal proliferation37
Telangiectasia34
StromaBizarre fibroblasts12
Stomach epitheliumAtrophy of specialised glands, increased numbers of apoptotic bodies14
Oesophageal epitheliumSquamous metaplasia and atrophy of submucous glands; villiform change of squamous mucosa11
22