Loss of heterozygosity (LOH) at chromosome 5 for each marker lesion combination in each of the haemangiomas (denoted UK1, UK2, and US1–4)
| Haemangioma sample number | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UK1 | UK2 | US1 | US2 | US3 | US4 | ||||||||
| Marker | Location (cM) | L1 | L2 | L1 | L2 | L1 | L2 | L1 | L2 | L1 | L2 | L1 | L2 |
| The results for each of the two dissections (L1 and L2) are given. | |||||||||||||
| +inf, LOH was infinite owing to complete loss of one allele; –, the marker was uninformative or marker analysis was attempted but failed. | |||||||||||||
| *LOH was greater than 2, denoting significant loss of the larger allele, or less than 0.5, denoting significant loss of the smaller allele. | |||||||||||||
| The map location of each marker is taken from the Marshfield map set 8 from Research GeneticsTM. | |||||||||||||
| Markers from chromosome 5p | |||||||||||||
| D5S2849 | 8 | 1.4 | – | 0.50* | 0.25* | – | – | 0.80 | 1.6 | 0.96 | 0.73 | 0.40* | 1.2 |
| D5S2505 | 13 | 1.2 | 1.6 | – | – | – | – | – | – | ||||
| GATA 134B03 | 38 | 1.9 | 1.5 | 1.0 | 1.0 | – | – | – | – | – | – | 1.0 | 0.89 |
| D5S1470 | 49 | – | – | 1.1 | – | – | – | – | – | – | – | – | – |
| Markers from chromosome 5q | |||||||||||||
| D5S1725 | 98 | 1.1 | 1.1 | 0.69 | 1.5 | – | – | – | – | – | – | – | – |
| D5S1453 | 123 | 0.74 | 0.99 | 1.4 | 1.5 | – | – | – | – | – | – | – | – |
| D5S2501 | 126 | 1.1 | 1.2 | 0.13* | – | 2.0* | 2.2* | – | – | – | +inf* | – | – |
| D5S1505 | 140 | 0.89 | 0.32* | 1.5 | 0.39* | – | – | – | – | – | – | 0.22* | 0.86 |
| D5S816 | 149 | 2.4* | 1.2 | 0.56 | 0.33* | 2.6* | 0.96 | +inf* | +inf* | ||||
| D5S1480 | 158 | – | 0.6 | 19* | 4.5* | 1.5 | 1.4 | – | – | – | – | – | – |
| D5S820 | 173 | – | – | – | – | 3.57* | 2.63* | 0.70 | 2.1* | ||||
| D5S1456 | 192 | – | – | – | – | 0.95 | 1.7 | 0.40* | 1.4 | 0.88 | 2.3* | ||