Presence of human papillomavirus (HPV) DNA in different cervical lesions as detected by PCR and visualised by elecrophoresis and type specific oligoprobes
HPV genotypes | |||||||||
---|---|---|---|---|---|---|---|---|---|
HPV DNA+/TS | Untyped HPV | HPV-16 | HPV-33 | HPV-31 | HPV-6 | HPV-18 | HPV-45 | HPV-11 | |
Untyped HPV: HPV DNA positive specimens visualised by electrophoresis but unrecognised by type specific oligoprobes. | |||||||||
HPV genotypes: HPV DNA positive specimens recognised by type specific oligoprobes in hybridisation assays. | |||||||||
ASCUS, atypical squamous cells of undetermined significance; HSIL, high risk squamous intraepithelial lesion; LSIL, low risk squamous intraepithelial lesion; TS, tested specimens. | |||||||||
Total specimens | 106/176 | 22/106 | 53/92 | 14/92 | 12/92 | 7/92 | 3/92 | 3/92 | 0/92 |
(60.2%) | (20.7%) | (57.6%) | (15.2%) | (13.0%) | (7.6%) | (3.3%) | (3.3%) | (0%) | |
ASCUS specimens | 12/44 | 5/12 | 2/8 | 2/8 | 3/8 | 1/8 | 0/8 | 0/8 | 0/8 |
(27.3%) | (41.7%) | (25.0%) | (25.0%) | (37.5%) | (12.5%) | (0%) | (0%) | (0%) | |
LSIL specimens | 23/43 | 8/23 | 6/17 | 4/17 | 2/17 | 4/17 | 0/17 | 1/17 | 0/17 |
(53.5%) | (34.8%) | (35.3%) | (23.5%) | (11.8%) | (23.5%) | (0%) | (5.9%) | (0%) | |
HSIL specimens | 71/89 | 9/71 | 45/67 | 8/67 | 7/67 | 2/67 | 3/67 | 2/67 | 0/67 |
(79.8%) | (12.7%) | (67.2%) | (11.9%) | (10.4%) | (3.0%) | (4.5%) | (3.0%) | (0%) |