Tumour immunoreactivity (TI) for nm23-H1 (compared with normal bronchial epithelium (NBE)) correlated with tumour cell dissemination (TCD) in all cases in which normal epithelium was identified on the tissue section
| n | TI<NBE | TI=NBE | TI>NBE | |
|---|---|---|---|---|
| In 32 of the 42 cases assessed by immunohistochemistry, normal bronchial epithelium could be identified on the same section. The intensity of immunoreactivity in the tumours in these 32 cases was compared to the respective normal bronchial epithelium. | ||||
| Bone marrow TCD absent | 20 | 6 | 8 | 6 |
| Bone marrow TCD detected | 12 | 6 | 6 | 0 |
| Pleural TCD absent | 26 | 8 | 12 | 6 |
| Pleural TCD detected | 6 | 4 | 2 | 0 |
| Lymphatic TCD absent | 14 | 7 | 4 | 3 |
| Lymphatic TCD detected | 18 | 5 | 10 | 3 |
| TCD absent in all systems | 9 | 2 | 4 | 3 |
| TCD detected in at least 1 system | 23 | 10 | 10 | 3 |
| Bone marrow and pleural TCD absent | 16 | 3 | 7 | 6 |
| TCD detected in bone marrow and/or pleura | 16 | 9 | 7 | 0 |