Correlation between cyclin D1 by flow cytometry, FISH, and immunohistochemistry
| Diagnosis | Flow cytometry | FISH | Immunohistochemistry |
|---|---|---|---|
| The 5D4 clone anti-cyclin D1 antibody (Immunotech) was used for flow cytometry; the DCS-6 clone anti-cyclin D1 antibody (Dako) was used for immunohistochemistry. | |||
| CLL, chronic lymphocytic leukaemia; FISH, fluorescence in situ hybridisation; MCL, mantle cell lymphoma. | |||
| MCL | Positive | Positive | Positive |
| MCL | Positive | Positive | Positive |
| MCL | Negative | Positive | Positive |
| MCL | Negative | Positive | Positive |
| CD5+B-NHL | Positive | Negative | Negative |
| CLL | Negative | Negative | Negative |
| CLL | Negative | Negative | Negative |
| CLL | Negative | Negative | Negative |
| Atypical CLL | Negative | Negative | Negative |