Table 1

Summary of the 10 cases of extramedullary myeloid tumours involving the mediastinum that have reported karyotypic data

CaseAge/ sexBlast cells in PBBone marrowFABImmunophenotypePleural involvementKaryotypeRemissionOutcomeRef
Chemo, chemotherapy; F, female; M, male; N/A, not available; N/D, not determined; PB, peripheral blood.
121/MYesYesM3N/DNoTetraploidyYesDeath, relapse14
245/FYesYesM2CD7/13/33+, HLA-DRNoDel (15)(q13q15)YesDeath, relapse15
34.5/MNoNoM4/M5CD33+, HLA-DR+Yest(9;11)(p22;q23)YesRemission 18+ months16
429/FNoNoM2CD34/33+, CD13NoDiploid/ near triploid/ near tetraploidNoRefractory death post allotransplant17
546/FYesYesM4CD34/7/33+, CD13NoDiploid/ near tetraploidYesDeath, relapse17
629/FYesYesM1N/ANoNear triploid/ near tetraploidYesDeath, relapse17
734/FNoNoM2CD33+, HLA-DR+Yes-10, -11NoDeath, refractory disease18
842/FNoNoM0CD7/34/33+, CD13+No15, +19, +20YesDeath, heart failure19
926/MNoYesRAEBCD33+YesNormalN/ADeath, post chemo20
1017/FNoN/DM1CD7/65/CD56+, HLA-DR+, CD13/33YesNear triploid/ near tetraploidNoDeathThis paper