Table 1

Baseline clinical and laboratory data in 72 outpatients with sickle cell disease and 50 controls enrolled in the study

Patients
VariableNormal UAERaised UAEControls
Data are number or mean (SD).
A/C, albumin to creatinine ratio; GFR, glomerular filtration rate measured by 51Cr-EDTA; Sβ, haemoglobin S with β thalassaemia; SC, haemoglobin SC; SS, sickle cell anaemia; 12UA, 12 hour urinary albumin excretion; UAE, urinary albumin excretion.
Number472550
Male/female21/2612/1325/25
Haemoglobinopathy34 SS, 4 Sβ, 9 SC20 SS, 3 Sβ, 2 SC
Age (years)29.19 (11.12)31.60 (9.98)34.0 (9.0)
Serum creatinine (mg/dl)0.50 (0.14)0.55 (0.17)
GFR (ml/min/1.73 m2)135.94 (42.28)120.59 (26.84)
12UA (mcg/min)6.55 (5.35)258.00 (411.71)
Urinary creatinine (mg/dl)68.66 (35.21)63.01 (21.66)124.7 (73.8)
A/C (mg/l/mg/dl)0.25 (0.27)4.80 (7.50)0.05 (0.03)