Table 2

IL-10 and TGFβ gene haplotype frequencies in 36 symptomatic B19 infected patients compared with controls

CytokineLocations of single 
 nucleotide polymorphismsHaplotype 
 (transcriptional level)Haplotype frequency in 
 B19 groupHaplotype frequency in controls*
*Data taken from Perrey et al.5 †Odds ratio, 4.8; 95% confidence interval, 1.01 to 16.9; p=0.02 (non-significant; p=0.18 after correction for multiple testing).
IL-10, interleukin 10; TGFβ1, transforming growth factor β.
IL-10−1082/−819/−592GCC/GCC12 (33.3%)99 (30.0%)
GCC/ACC7 (19.4%)68 (20.6%)
GCC/ATA8 (22.2%)70 (21.1%)
ACC/ACC4 (11.1%)27 (8.2%)
ACC/ATA3 (8.3%)41 (12.4%)
ATA/ATA2 (5.5%)25 (7.6%)
Total=36Total=330
TGFβ1+869(c10)/+915(c25)TG/TG14 (38.9%)44 (41%)
TG/CG11 (30.6%)38 (36%)
TG/CC3 (8.3%)13 (12%)
CG/CG (intermediate)6 (16.7%)†5 (5%)
TG/TC0 (0%)0 (0%)
CG/CC2 (5.6%)6 (6%)
TC/TC0 (0%)0 (0%)
TC/CC0 (0%)0 (0%)
CC/CC0 (0%)1 (1%)
Total=36Total=107