Table 1

Detection of HPV DNA in bronchial papillomas and carcinomas

			HPV type detected
Type of lesion	Technique	No. of cases	6	6/11	11	16	16/18	18	Other	Total (%) HPV+	First author (year)
Three additional cases with HPV-31/33/35; †two additional cases with HPV-31/33/35; ‡HPV-31 and HPV-33; §ISH for HPV-6/11, HPV-16/18, and HPV-31/33/51; ¶oncogenic types in HCII assay; *HPV-6/16; ††HPV-11/16; ‡‡triple infections.
AdC, adenocarcinoma; AnSCC, anaplastic carcinoma; ASC, adenosquamous carcinoma; ASSC, alveolar carcinoma; DB, dot blot hybridisation; EM, electron microscopy; FISH, filter in situ hybridisation; HCII, hybrid capture II; ISH, in situ hybridisation; LCC, large cell carcinoma; ND, not defined; PCR, polymerase chain reaction; SB, Southern blot hybridisation; SCC, small cell carcinoma; SCP, squamous cell papilloma; SQC, squamous cell carcinoma; SQM, squamous cell metaplasia.
SQC	SB	9								0	Stremlau (1985)³⁴
LCC	SB	7								0
ASC	SB	2								0
ASC	SB	5				1				20
SQC	SB	1		1						100	Byrne (1987)³⁵
SQC	ISH	99					5			5	Syrjänen(1987)³⁶
SCP	EM	1								100	Trillo (1988)³³
SQC	ISH	131	2			7				7	Syrjänen (1989)³⁷
SCP	ISH	1		1						100	Kerley (1989)³⁸
SCP	ISH	15				1				7	Carey (1990)³⁹
SQM	ISH	10	1							10	Bejui-Thivol (1990)⁴⁰
SQC	ISH	33	1	1	1			3		18
SQC	ISH	1		1						100	Bejui-Thivol (1990)⁴¹
SQC	FISH	5					2			40	Kulski (1990)⁴²
SCP	ISH	6		6						100	Popper (1992)⁴³
SQC	ISH	5					5*†		100
SQC	ISH	1	1							100	DiLorenzo (1992)⁴⁴
SQM	ISH	17		1			1			12	Yousem (1992)⁴⁵
SQC	ISH	20		1			2			15
ASC	ISH	12								0
ASSC	ISH	16								0
SQC	ISH	4								0
LCC	ISH	6		1						17
SCP	ISH	2		2						100
SQC	PCR, SB	29				3		0		10	Ogura (1993)⁴⁶
SCP	ISH	1		1						100	Katial (1994)⁴⁷
SQC	PCR, ISH	49		1	5	1				14.2	Liu (1994)⁴⁸
SCP	PCR	20	3		6			2		55	Popper (1994)⁴⁹
SQC	PCR	11						1		9
SQC, AdC	PCR	85								0	Shamanin (1994)⁵⁰
LSSC	PCR	7								0	Szabo (1994)⁵¹
SQC	PCR	40								0
SQC	PCR, ISH	49		4		2	2			16.3	Xing (1994)⁵²
SQC	PCR	66			3	1			2	9	Al-Ghamdi (1995)⁵³
SQC	DB, SB, PCR	10						1		10	Kinoshita (1995)⁵⁴
AdC	DB, SB, PCR	26						2		9
SQC	DB, PCR	50				10	1	5		32	Li (1995)⁵⁵
ASSC	ISH, PCR	22	2	3		1		1	10‡	36	Nuorva (1995)⁵⁶
SQC	DB. PCR	27				7	1	5		48	Qingquan (1995)⁵⁷
AdC	DB, PCR	16				2	0	0		12
SQC	DB, PCR	2				1	0	0		50
ASC	DB, PCR	5								0
SCC	PCR	8						1		12.5	Sagawa (1995)⁵⁸
SQC	PCR	18		1		1				11	Thomas (1995)⁵⁹
SQC	PCR	34								12	Zhang (1995)⁶⁰
SQC	PCR	9				9				100	Da (1996)⁶¹
SQC	PCR	16				8				50
AdC	PCR	12				5				42
AdC	PCR	4		1				1		50	Thomas (1996)⁶²
LCC	PCR	2								0
SQC	PCR	7		2						28
SQC	PCR, ISH	73		11			26	4		56	Hirayasu (1996)⁶³
AdC	PCR	41				2		6		20	Noutsou (1996)⁶⁴
SQC	PCR	41				2		2		10
LCC	PCR	10			3				2‡	20
SQC	PCR	7								0
SQC	ISH, PCR	28	5	4		6		4	1‡	67	Soini (1996)⁶⁵
AdC	ISH, PCR	12	1		2	2		3	5‡	75
SQC	ISH, PCR	3								0
SQC	PCR	ND	ND		ND	ND				79	Nakazato (1997)⁶⁶
SQC	ISH, PCR	32								0	Welt (1997)⁶⁷
SQC	ISH, PCR	6								0
SQC	ISH, PCR	34						2		6	Bohlmeyer (1998)⁶⁸
SCP	ISH, PCR	14					5§			36	Flieder (1998)³⁰
SCC	PCR, SB	52		6			11		ND	69	Papadopoulou (1998)⁶⁹
ASC	ISH, PCR	23					18		ND	78	Tsuhako (1998)⁷⁰
SCC	PCR	35								0	Wistuba (1998)⁷¹
SQC	PCR, ISH	31								0	Gorgoulis (1999)⁷²
AdC	PCR, ISH	32								0
LCC	PCR, ISH	5								0
SQC	PCR	1					1			100	Hennig (1999)⁷³
SQC	ISH, PCR	75	12		1††	18 (5)**	1			49	Hennig (1999)⁷⁴
AdC	PCR, EM	285					1	ND		0.4	Hiroshima (1999)⁷⁵
SCP	PCR	1			1					100	Kawaguchi (1999)⁷⁶
SQC	HCII	185					5¶			2.7	Clavel (2000)⁷⁷
SCP	ISH, PCR	1	1			1				100	Harada (2000)⁷⁸
SQC	ISH, PCR	44					ND			57	Iwamasa (2000)⁷⁹
SQC	ISH, PCR	157	9		16	22		25	5‡‡	49	Miyagi (2000)⁸⁰
SQC	ISH, PCR	141					77			55	Cheng (2001)⁸¹
SQC	ISH	26		1			2			11.5	Kaya (2001)⁸²
SQC	ISH	22					1			4.5	Miasko (2001)⁸³
AdC	ISH	13		1						7.6
LCC	ISH	5					1			20
SQC	ISH, PCR	59					29ND			49	Miyagi (2001)⁸⁴
AdC	ISH, PCR	62					12ND			19.4