Tissue microarray analysis of the expression of CD44 standard isoform (CD44s) and its variant isoforms CD44v4, CD44v6, and CD44v9 in diffuse large B cell lymphoma (DLBCL)
CD44s | CD44v6 | CD44v9 | |||||
---|---|---|---|---|---|---|---|
Lymphoma subtype | 10–20% | 20–70% | >70% | 10–20% | 20–70% | >70% | >70% |
Positive cases out of evaluable cases are shown. | |||||||
ABC, activated B cell-like; FL, follicular lymphoma; GC, germinal centre B cell-like; SLL, small lymphocytic lymphoma. | |||||||
All de novo DLBCLs | 12/73 | 19/73 | 28/73 | 14/75 | 5/75 | 4/75 | 15/79 |
DLBCL ABC type | 8/23 | 5/23 | 10/23 | 5/22 | 2/22 | 2/22 | 4/22 |
DLBCL GC type | 4/22 | 8/22 | 7/22 | 2/22 | 2/22 | 0/22 | 7/22 |
Transformed FL | 0/6 | 1/6 | 3/6 | 0/6 | 0/6 | 0/6 | 0/6 |
Transformed SLL | 1/2 | 1/2 | 0/2 | 0/2 | 1/2 | 0/2 | 1/2 |