Table 1

Modification of the Rushton scoring system

Factor categoryTotal scoreFactor breakdownScore
The maximum score was 500.
*Items included in the minimum accepted score; †a score of 50 was given for any of the following metabolic tests: frozen tissue, acyl carnitine screen, organic acid screen, skin fibroblast culture, or basic metabolic screen.
CSF, cerebrospinal fluid; PCR, polymerase chain reaction.
Weights and measures*80*Body weight20
Crown rump20
Crown heel20
Head circumference20
Main organ weights*40*Heart8
Lungs8
Liver8
Kidney8
Brain8
Minor organ weights15Spleen5
Adrenals5
Thymus5
Normal values20Heart, lungs, liver, kidney, brain4 each
Histology main organ*50*Heart10
Lungs10
Liver10
Kidney10
Brain10
Histology minor organ30Spleen10
Adrenals10
Thymus10
Radiology100100
Microbiology50Swabs20
Blood culture10
PCR10
CSF10
Biochemistry2020
Toxicology*35*35
Virology1010
Metabolic investigations†5050
Total maximum score500500
Minimum accepted score205205