Telomerase components and HPV in cervical scrapings of women referred for a borderline, mild, or moderate dyskaryotic smear
| Histology | ||
|---|---|---|
| CIN 0/I n=22 | CIN II/III n=28 | |
| Telomerase activity was classed as present when 10 U/μg protein was found. *The quality of 3 samples was too poor to analyse. | ||
| CIN, cervical intraepithelial neoplasia; HPV, human papillomavirus; hTERT, human telomerase reverse transcriptase mRNA; hTR, human telomerase RNA. | ||
| Telomerase activity | 1 (4.5%) | 0 |
| hTR expression | 22 (100%) | 22* (88%) |
| hTERT mRNA expression | 4 (18%) | 7* (28%) |
| High risk HPV | 11 (50%) | 22 (79%) |