Table 5

Radiation related pathological alterations

Ulceration of urothelium
Urothelial cell enlargement, mutinucleation, and cytoplasmic vacuolisation, but nuclear to cytoplasmic ratios remain low
Acute and/or chronic inflammation of the lamina propria
Nodules of squamoid epithelium (reactive)
Giant cell cystitis
Bladder wall fibrosis (late stage)