Comparison of comparative genomic hybridisation results and clinicopathological variables between retinoblastomas with low level and those with high level chromosomal instability (CIN)
| Low level CIN (<6 events) n=7 | High level CIN (≥6 events) n=6 | p Value | |
|---|---|---|---|
| NS, not significant. | |||
| Events (mean) | 1.7 | 14.2 | 0.02 |
| Gains (mean) | 1.3 | 9.5 | 0.03 |
| Losses (mean) | 0.4 | 4.7 | 0.02 |
| Age (mean, in months) | 10.1 | 23.3 | NS |
| Male to female ratio | 1.3:1 | 5:1 | NS |
| Hereditary (%) | 57 | 33 | NS |
| Bilateral (%) | 57 | 17 | NS |
| Undifferentiated (%) | 57 | 83 | NS |
| Death of disease (%) | 14 | 17 | NS |