Table 4

Monitor and reference INR for 535 target samples at 10 centres

POCT system	Species specific IRP	Mean reference INR	Lyophilised plasma calibration	Mean monitor INR	Mean % difference	CI for mean % difference	p Value (paired t test)
Geometric means of reference and monitor INR values, percentage difference in geometric mean INR, corresponding 95% confidence intervals (CI), and p value are given.
INR, international normalised ratio; IRP, international reference preparation; POCT, point of care testing; RBT/90, rabbit plain international reference preparation; rTF/95, human recombinant international reference preparation.
CoaguChek Mini	RBT/90	2.50	Artificially depleted	2.77	10.8	8.9 to 12.7	<0.0001
			Individual coumarin	2.56	2.2	0.5 to 3.9	0.0099
			Pooled coumarin	2.63	5.0	3.3 to 6.8	<0.0001

TAS PT-NC	rTF/95	2.46	Artificially depleted	2.16	−12.0	−13.2 to −10.8	<0.0001
			Individual coumarin	2.13	−13.4	−14.5 to −12.2	<0.0001
			Pooled coumarin	2.14	−12.9	−14.1 to −11.7	<0.0001