Table 1

The fasting lipid profile of the patients and controls (mmol/l)

TCTGHDL-CApo A1Apo B
Apo, apolipoprotein; HDL-C, high density lipoprotein cholesterol; HTD, homozygous Tangier disease; hTD, heterozygous Tangier disease; TC, total cholesterol; TG, triglycerides. The “V + a number” abbreviations refer to the family tree shown in fig 1.
Proband
    Case 1 (V10) HTD2.01.60.050.52.2
Siblings
    Case 2 (V9) HTD1.43.10.05<0.52.0
    Case 3 (V16) HTD1.33.10.05<0.51.7
    Case 4 (V17) hTD2.90.90.51.91.8
    Case 5 (V14) hTD3.40.70.72.61.7
Controls
Mean (SD)5.3 (0.9)1.2 (0.3)1.3 (0.3)3.8 (0.8)3.5 (1.3)