Table 1

Causes of hyperprolactinaemia

Physiological (pregnancy, stress, nipple stimulation, coitus)
Pituitary prolactinoma
Any pituitary/hypothalamic tumour that compresses the pituitary stalk
Idiopathic hypersecretion
Primary hypothyroidism
Pharmacological causes (phenothiazines, butyrophenones, pimozide, cimetidine, methyldopa)
Polycystic ovarian syndrome
Renal/liver failure
Traumatic or neoplastic lesions of the thorax or spine
Ectopic production of prolactin by extrapituitary tumour