Characteristic features of meningococcal disease in patients with complement deficiency
| Feature | Comment |
|---|---|
| A finding of any of these features should prompt testing of complement function. | |
| Unusual serogroup | Infection with an unusual serogroup organism such as W135 is strongly suggestive of complement deficiency |
| Recurrent disease | This seems to be particularly associated with terminal complement component deficiency |
| Family history | Complement deficiency inheritance is usually autosomal recessive or X linked (see text) |