Table 2

α Globin genotype and α thalassaemia frequencies from five different regions in Guangdong Province

Genotype	Guangzhou		Zhanjiang		Zhuhai		Shaoguan		Shantou		Total
Genotype	N	%	N	%	N	%	N	%	N	%	N	%
*Two samples with Hb Bart’s (values of 2.17% and 5.81%, respectively) could not be determined by Southern blotting because of DNA degeneration.
−−^SEA/αα	35	39.8	49	55.7	72	52.6	48	48.0	17	29.3	221	46.9
−α^3.7/αα	38	43.2	24	27.3	41	29.9	41	41.0	28	48.3	172	36.5
−α^4.2/αα	12	13.7	13	14.8	16	11.7	5	5.0	7	12.1	53	11.3
−−^THAI/αα	0	0	0	0	0	0	0	0	2	3.5	2	0.4
α^CSα/αα	1	1.1	1	1.1	4	3.0	3	3.0	1	1.7	10	2.2
α^QSα/αα	0	0	0	0	1	0.7	0	0	0	0	1	0.2
−−^SEA/−α^3.7	1	1.1	0	0	0	0	1	1.0	0	0	2	0.4
−−^SEA/α^QSα	0	0	0	0	1	0.7	0	0	0	0	1	0.2
−−^SEA/−−^SEA	0	0	1	1.1	0	0	2	2.0	1	1.7	4	0.9
−−^11.1/αα	1	1.1	0	0	0	0	0	0	0	0	1	0.2
α1CD118 (+TCA)	0	0	0	0	0	0	0	0	1	1.7	1	0.2
ζ-α Gene deletion	0	0	0	0	1	0.7	0	0	0	0	1	0.2
Undetermined*	0	0	0	0	1	0.7	0	0	1	1.7	2	0.4
Total	88	100	88	100	137	100	100	100	58	100	471	100