Semiquantitative results of immunohistochemistry for perforin and granzyme B in IPF
| Patient | Perforin | Granzyme B | ||||||
|---|---|---|---|---|---|---|---|---|
| Epi | Fib | Macro | Lymph | Epi | Fib | Macro | Lymph | |
| Grades of IPF: 0, no positive cells; 1, <10% of cells positive; 2, 10–49% of cells positive; 3, >50% of cells positive. | ||||||||
| Epi, epithelium; Fib, fibroblast; IPF, idiopathic pulmonary fibrosis; Lymph, lymphocyte; Macro, macrophage. | ||||||||
| IPF | ||||||||
| 1 | 1 | 0 | 0 | 2 | 1 | 0 | 0 | 1 |
| 2 | 1 | 1 | 0 | 3 | 1 | 1 | 1 | 1 |
| 3 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 |
| 4 | 1 | 0 | 0 | 3 | 1 | 1 | 0 | 3 |
| 5 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
| 6 | 1 | 1 | 0 | 2 | 1 | 1 | 0 | 2 |
| 7 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 2 |
| 8 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2 |
| Controls | ||||||||
| 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |