Table 1

Detection of HPV DNA in tonsillar carcinomas

TechniqueNo of positive cases/totalHPV types
6/11161816/1816/333133XFirst author (year)
*Triple infection with HPV types 6, 16, and 18; †one infection with several HPV types 6, 18, 31, and 35; ‡double infections with HPV types 5/16, ADX1/16; §HPV-12, HPV-59; ¶one unidentified and HPV-59; **includes also tumours of the lingual tonsils.
HPV, human papillomavirus; ISH, in situ hybridisation; PCR, polymerase chain reaction; SB, Southern blotting.
SB2/711Brandsma (1989)33
SB1/11*Ishibashi (1990)34
ISH6/286Niedobitek (1990)29
SB1/1Bercovitch (1991)35
ISH5/5Arndt (1992)30
PCR10/104132Snijders (1992)5
PCR12/147122Snijders (1994)36
PCR2/3Brachman (1992)37
PCR, SB, Virapap3/63Watanabe (1993)38
PCR, SB1/41Ogura (1993)39
PCR2/42Lewensohn-Fuchs (1994)40
PCR3/7NDBrandwein (1994)41
PCR, SB9/1581Paz (1997)9
PCR, SB1/11Turazza (1997)42
PCR, SB11/21812Andl (1998)43
PCR, SB19/44340Schwarz (1998)44
PCR14/221112Wilczyski (1998)45
PCR2/21*1*Badaracco (2000)46
PCR6/136†Lopez-Lizarraga (2000)47
SB1/11Ishiji (2000)48
PCR2/411Badaracco (2000)49
PCR32/52Gillison** (2000)7
PCR26/60261Mellin (2000)6
PCR12/22111Mellin (2002)3
PCR14/2412‡11Klussman (2001)50
PCR, SB24/5221¶Strome (2002)51
Ringström (2002)52
Total (%)221/432 (51)7 (3)186 (84)7 (3)3 (1.4)6 (2.8)9 (4.6)13 (6)