Detection of HPV in normal tonsillar mucosa or benign lesions
Type of lesion | Technique | No of cases | 6/11 | 16 | 18 | 31 | 33 | First author (date) |
---|---|---|---|---|---|---|---|---|
In total, 17/200 (8.5%) samples were HPV positive. | ||||||||
HPV, human papillomavirus; ISH, in situ hybridisation; PCR, polymerase chain reaction; SB, Southern blotting. | ||||||||
Tonsillitis | SB | 0/20 | Brandsma (1989)33 | |||||
Chronic inflammatory disease | ISH | 0/30 | Niedobitek (1990)29 | |||||
Tonsillitis | PCR | 0/7 | Snijders (1992)5 | |||||
Normal posterior tonsillar pilar | PCR, SB | 1/3 | 1 | Smith (1993)60 | ||||
Chronic tonsillitis | PCR, SB | 4/28 | 4 | Watanabe (1993)38 | ||||
Adenoid hyperplasia and chronic tonsillitis | PCR, SB | 0/8, 5/38 | 5 | Fukushima (1994)61 | ||||
Condyloma | SB | 1/1 | 1 | Tominaga (1996)62 | ||||
Normal mucosa | SB | 3/3 | 3 | Tominaga (1996)62 | ||||
Chronic tonsillitis | PCR | 0/14 | Klussmann (2001)50 | |||||
Tonsillar hyperplasia | PCR, SB | 3/48 | 3 | Strome (2002)51 |