The presence of human papillomavirus (HPV) DNA in patients with cervical cancer
| HPV DNA positive cervical lesions (n = 60) | HPV DNA positive lymph nodes (n = 31) | p Value | |
|---|---|---|---|
| Mean age (SD) | 50.6 (10.2) | 48.2 (9.2) | 0.06 |
| FIGO stage | |||
| IA | 4 | 1 | 0.44 |
| IB | 27 | 14 | |
| IIA | 21 | 13 | |
| IIB | 8 | 3 | |
| Histopathology | |||
| Squamous cell carcinoma | |||
| Carcinoma in situ | 5 | 0 | 0.09 |
| Large cell keratinising | 5 | 3 | |
| Large cell non-keratinising | 46 | 25 | |
| Adenocarcinoma | 4 | 3 | |
| Depth of cervical invasion | |||
| Carcinoma in situ and microinvasion to 3 mm | 6 | 1 | 0.18 |
| Invasion 3–10 mm | 10 | 5 | |
| Invasion >10 mm | 44 | 25 | |
| Volume of primary lesion | |||
| <1 cm3 | 11 | 3 | 0.03 |
| 1–10 cm3 | 10 | 3 | |
| >10 cm3 | 39 | 25 | |
| Corpus invasion | |||
| Not over internal isthmus | 46 | 21 | 0.09 |
| Over internal isthmus | 14 | 10 | |
| Vaginal invasion | |||
| No | 34 | 13 | 0.01 |
| Yes | 26 | 18 | |
| Parametrial invasion | |||
| No | 53 | 26 | 0.26 |
| Yes | 7 | 5 | |